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Opportunity at National Institute of Standards and Technology (NIST)

Quantitative Photoacoustic Imaging and Spectroscopy

Location

Physical Measurement Laboratory, Applied Physics Division

RO# Location
50.68.62.B8226 Boulder, CO

Please note: This Agency only participates in the February and August reviews.

Advisers

name email phone
Kimberly A. Briggman kbriggma@nist.gov 303.497.7287
Jeeseong Hwang jch@nist.gov 303.497.6588

Description

Optical techniques are fundamentally limited to near-surface imaging or to low resolution diffuse light scattering applications as the optical wavelengths of light significantly scatter through thick tissue, preventing the backscattered light from refocusing for precise image reconstruction. However, in photoacoustic or optoacoustic imaging, the absorption of light by existing endogenous molecules induces an acoustic wave which is not as susceptible to scattering as the incident optical wavelengths. The goal of this research is to develop and apply measurement technologies and standards to enable quantitative and functional photoacoustic imaging of biological samples with enhanced spatial and spectral resolutions. 

 

Ongoing research in this area involves: (1) performing photoacoustic microscopy, tomography, and spectroscopy; (2) employing novel optical sources including pulsed LEDs, supercontinuum lasers, frequency comb lasers for quantitative photoacoustic imaging and spectroscopy; (3) wave-front shaping for enhanced light focusing through a scattering medium (4) calibrating broadband and high frequency ultrasound sensors for their quantitative applications; (5) developing tissue-mimicking phantom standards; and (6) numerical simulating photoacoustic mechanisms and signal processing algorithms on various platforms.         

Keywords:
photoacoustic microscopy; photoacoustic spectroscopy; photoacoustic tomography; superresolution; functional imaging; label-free; quantitative imaging; wavefront engineering

Eligibility

Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral applicants

Stipend

Base Stipend Travel Allotment Supplementation
$74,950.00 $3,000.00
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