NRC Research Associate Programs
Fellowships Office
Policy and Global Affairs

Participating Agencies - NIST

Opportunity at National Institute of Standards and Technology (NIST)

Drug Toxicity Measurements with Tissues-on-chips and Microphysiologic Systems

Location

Physical Measurement Laboratory, Microsystems and Nanotechnology Division

RO# Location
50.68.02.C0078 Gaithersburg, MD 20899

Please note: This Agency only participates in the February and August reviews.

Advisers

name email phone
Mandy Brigitte Esch mandy.esch@nist.gov 301.975.8575

Description

Postdoctoral research opportunities are available for developing tissues-on-chips and multi-organ microphysiological systems (MPS) that realize reliable and accurate drug testing of new drug candidates. Our laboratory has developed microphysiological systems that operate with small amounts of recirculating cell culture medium (Lab on a Chip 16(14): 2719-2729, 2016, and Microphysiol Syst. 2020 Jun; 4: 10.21037/mps-19-8) that will make toxic metabolite detection more sensitive. Recent work includes a new, pumpless liver/heart system. NRC postdocs can propose to work on optimizing MPS designs (potentially with integrated, microfabricated sensors), developing new tissues-on-chips, developing MPS for new organ combinations, and testing drug candidates in collaboration with NIH with any of the developed devices.

 

Keywords:
Body-on-a-chip; Organ-on-a-chip; Tissues-on-chips, Microfluidics, microphysiologic systems; MPS; Biosensors; Nanofabrication; Liver; Toxicity; Drug;

Eligibility

Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral applicants

Stipend

Base Stipend Travel Allotment Supplementation
$74,950.00 $3,000.00
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