Clinical Genetics
Material Measurement Laboratory, Biomolecular Measurement Division
NIST only participates in the February and August reviews.
Standards for genetic testing are needed to support the clinical testing community and manufacturers of working standard materials. Challenges lie in developing relevant standards in a timely fashion to support new clinical targets and commercial assays. Common methods of characterization include copy number determination by quantitative PCR and digital PCR, as well as sequencing by Sanger and next-generation platforms. Projects focus on the development of nucleic acid-based standard materials and the application of emerging technologies to assist clinical testing efforts.