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Relationship of Prenatal Toxicity to Postnatal Functional Deficits


Environmental Effects Research Laboratory-FFP, Toxicity Assessment Division - FFP

RO# Location
AC.02.08.B0340 Research Triangle Park, NC 27711


Name E-mail Phone
Lau, Christopher Si-Lung 919.541.5097


The ability of numerous agents to induce embryonic and/or fetal toxicity in mammals is well documented. The biological significance of some of these toxic manifestations (e.g., reduced fetal weight, enlarged renal pelvis, supernumerary ribs, enlarged cerebral ventricles, and wavy ribs) is relatively unknown. Solving this problem will require careful monitoring of prenatal insults and correlative evaluations of physiological and biochemical functions of the neonate during its early postnatal life. Key organ systems to be investigated include the cardiac, renal, pulmonary, and central nervous system.


Central nervous system; Chemical toxicology; Developmental toxicology; Hepatic system; Immunotoxicology; Neurotoxicology; Perinatal period; Reproductive toxicology;


Citizenship:  Open to U.S. citizens and permanent residents
Level:  Open only to Senior applicants
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