The National Academies Logo
Research Associateship Programs
Fellowships Office
Policy and Global Affairs

Participating Agencies - EPA/FFP

  Sign InPrintable View

Opportunity at EPA/Faculty Fellowship Program (EPA/FFP)

Bioaccessibility and Bioavailability of Metals in Contaminated Soils


National Exposure Research Labortory-FFP, Human Exposure/Atmospheric Sci Div - FFP

RO# Location
AC.01.03.B7049 Research Triangle Park, NC 27711


Name E-mail Phone
Bradham, Karen 919 541 9414


NERL’s Method Development and Applications Branch has a research opportunity to investigate the bioavailability of metals including nanomaterials and explore the relationship of metal bioaccessibility and bioavailability in environmental media. This research effort will complement ongoing research to develop techniques to investigate the bioavailability of nanomaterials,elucidate the speciation of metals in soils, and relate metal speciation and soil characteristics to bioavailability. Work will involve (1) evaluating the bioavailability of nanomaterials, (2) building a data base of in-vitro bioaccessibility data using an extraction test to assess the potential bioavailability of metals in soils, (3) development of in-vitro bioaccessibility extractions tests to assess the potential bioavailability of arsenic in soil, (4) research in support of in-vivo animal feeding studies, and (5) evaluation of the relationship between the bioavailability and bioaccessibility results. Knowledge of metal bioavailability and chemistry in soils is necessary. Development of improved extraction methods, in vivo models, and laboratory analyses will be encouraged.



Bradham KD, et al: Environmental Health Perspectives 119: 1629, 2011

Van de Wiele T, et al: Environmental Health Perspectives 118: 1004, 2010


Bioavailability; Bioaccessibility; In vitro; In vivo; Solubility; Soils; Lead; Soil chemistry; Arsenic;


Citizenship:  Open to U.S. citizens and permanent residents
Level:  Open only to Senior applicants
Copyright © 2014. National Academy of Sciences. All rights reserved. 500 Fifth St. N.W., Washington, D.C. 20001.
Terms of Use and Privacy Statement.