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Opportunity at Davies Teaching Fellowships (ARL/USMA)

Bacteriophage for Biothreat Treatment and Remediation

Location

US Military Academy-FFP, Photonics Research Associateship-FFP

RO# Location
AA.33.01.C0138 West Point, NY 10996

Advisers

Name E-mail Phone
Barnhill, Jason jason.barnhill@westpoint.edu 808-352-3186

Description

This research aims to identify novel bacteriophages with the end goal of utilizing them as clinical therapeutics and as agents for remediation of bioweapon attacks. Initial emphasis will be on bacteriophage discovery and the effects of phage exposure on multidrug resistant bacterial strains. Novel phages will be sequenced and analyzed to determine if they carry pathogenicity islands or novel enzymes that could be utilized apart from phage activity. Novel phages that meet certain progression criteria will then be tested for basic immunogenicity, prophylactic, and therapeutic effects in mouse models at the Walter Reed Army Institute of Research (WRAIR). The prospective researcher should have experience with PCR, genome sequencing, sequence analysis, bacterial culture, molecular pathogenesis, data collection and analysis, and report writing. The post-doc will train, mentor, and work closely with West Point cadets.

 

Keywords:
Bacteriophage; Bio-threat; Multidrug Resistant Bacteria; Therapeutic; Remediation

Eligibility

Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral applicants
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