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Opportunity at U.S. Army Medical Research & Materiel Command (AMRMC)

Bench to Bedside: Postdoctoral Fellowship Utilizing Translational Medicine in Ocular Trauma

Location

U.S. Army Institute of Surgical Research, US Army Institute of Surgical Research

RO# Location
97.40.00.B8414 Fort Sam Houston, TX 782346315

Advisers

Name E-mail Phone
Zamora, David Omar david.o.zamora.civ@mail.mil 210.539.9457

Description

The objective of our research program is to develop and evaluate regenerative medicine treatments for the anterior portion of the traumatized eye. Our research portfolio is designed to fill existing capability gaps in current ocular therapies. Some specific lines of research include evaluating (1) stem cell therapies to regenerate corneal tissue, (2) tissue engineered surgical grafts containing corneal cells, (3) corneal wound healing and adapting currently approved FDA products to facilitate healing, and (4) developing magnetic nanoparticle cell therapies to specifically target traumatized or diseased structures in the eye. Research employs large and small animal models, tissue and cell culture, histology, and molecular biology techniques. The ultimate goal of this research is to better understand the potential mechanisms involved in battlefield ocular trauma, and develop new treatment modalities to improve vision restoration. Emphasis is placed on transitioning products from pre-clinical to clinical testing in a collaborative environment involving researchers and clinicians.

 

References

Cornell LE, et al: Magnetic Nanoparticles as a potential vehicle for corneal endothelial repair. Journal of Military Medicine 181(5): 232-239, 2016

Wehmeyer JL, Natesan S, Christy RJ: Development of a Sterile Amniotic Membrane Tissue Graft Using Supercritical Carbon Dioxide. Tissue Engineering Part C Methods 21(7): 649-659, 2015

 

Keywords:
Eye; Biomaterials; Ocular; Trauma; Nanomaterials; Endothelium; Cornea; Limbus; Epithelium;

Eligibility

Citizenship:  Open to U.S. citizens, permanent residents and non-U.S. citizens
Level:  Open to Postdoctoral and Senior applicants
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