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Opportunity at U.S. Army Medical Research & Materiel Command (AMRMC)

Improving Outcomes of Extremity Trauma through Infection Control and Bone Regeneration

Location

U.S. Army Institute of Surgical Research, US Army Institute of Surgical Research

RO# Location
97.40.00.B7501 Fort Sam Houston, TX 782346315

Advisers

Name E-mail Phone
Wenke, Joseph C joseph.c.wenke.civ@mail.mil 210 539 9426

Description

This Research Opportunity is in the Extremity Trauma and Regenerative Medicine Task Area of the US Army Institute of Surgical Research. Extremities are the most commonly injured part of the body and these injuries cause approximately two-thirds of the hospital costs and disability payments. Open fractures are one of the more frequent wounds of battlefield injured soldiers and these injuries are plagued by complications such as infection and nonunion.

The research will focus on tissue regeneration and/or infection control in orthopedic trauma with the primary objective to reduce morbidity associated with traumatic extremity wounds. The Associate will take a leading role in developing novel therapies to prevent or reduce biofilms and targeted drug delivery. Various in vitro biofilm models and small and large animal infection models are utilized within our laboratory to evaluate promising therapies. Associates may also focus on cell or growth factor delivery strategies to injured tissue and approaches to improve stem cell engraftment in host tissue. We have many academic and industry partners, which provides ample opportunity for interaction and transfer of new approaches and technologies. There will also be opportunities to work with clinicians to develop and evaluate therapies to some of our most daunting clinical problems. This will provide the Associate with a clinical perspective, and our translational focus will provide experience working with relevant preclinical models.

 

Keywords:
Biomaterials; Biofilm; Regenerative medicine; Tissue engineering; Drug delivery; Cell biology; Infection; Translational research;

Eligibility

Citizenship:  Open to U.S. citizens, permanent residents and non-U.S. citizens
Level:  Open to Postdoctoral and Senior applicants
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