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Opportunity at U.S. Army Medical Research & Materiel Command (AMRMC)

Genomic and Proteomic Biomarkers

Location

Telemedicine & Advanced Technology Research Center

RO# Location
97.21.00.B6389 Frederick, MD 2l7025012

Advisers

Name E-mail Phone
Reifman, Jaques jaques.reifman.civ@mail.mil (301) 619-7915

Description

To reach our objectives, we are developing genomic and proteomic biomarkers. This objective relates to the need to develop more effective field-deployable assays and biosensors for detection and diagnosis of human exposure to a large array of existing and bio-engineered pathogens and infectious agents. This research will be achieved by porting, modifying, and developing scalable software and algorithms that will speedup the identification of DNA and protein biomarkers (“fingerprints”) that are unique of specific biothreats and indigenous agents. These biomarkers are essential for the design of assays that respond faster with higher sensitivity, allow multiplexing and identification of multiple threats in a single platform, provide independent routes of confirmation, and identify bio-engineered threat agents that foil conventional detection methods. This goal addresses the fact that improved diagnostic assays must be developed to reduce the number of potential casualties and expedite their treatment through the use of the most appropriate medical countermeasures. Prospective applicants should have a strong background in computer science, computational biology, and computational chemistry.

 

Keywords:
Genomic; Proteomic; Biomarkers; DNA fingerprints; Data mining; Pattern recognition;

Eligibility

Citizenship: 
Level: 
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