RAP opportunity at U.S. Army Medical Research & Materiel Command AMRMC
Burkholderia pseudomallei Animal Modeling for Future Testing of Novel Medical Countermeasures
Location
U.S. Army Medical Research Institute of Infectious Diseases, US Army Medical Research Insti Infec Diseases
| opportunity |
location |
|
| 97.20.00.B8337 |
Fort Detrick, MD 217025011 |
Advisers
| name |
email |
phone |
|
| Christopher Kevin Cote |
christopher.k.cote.civ@health.mil |
301.619.4936 |
Description
This project involves developing animal models for Burkholderia mallei and Burkholderia pseudomallei, the etiological agents of the diseases glanders and melioidosis. There are currently no effective vaccines against either of these bacteria and antibiotic resistance continues to be a concern for the biodefense community. Our work predominantly deals with developing mouse models of infection, characterizing the pathogenesis of the bacteria, and documenting the host immune response to the ensuing infection.
Reference
Welkos SL, et al: Characterization of Burkholderia pseudomallei strains using a murine intraperitoneal infection model and in vitro macrophage assays. PLoS One 10(4): e0124667, 2015
key words
Glanders; Burkholderia mallei; Animal model; Burkholderia pseudomallei; Melioidosis; Mice;
Eligibility
Citizenship:
Open to U.S. citizens, permanent residents and non-U.S. citizens
Level:
Open to Postdoctoral and Senior applicants
Stipend
| Base Stipend |
Travel Allotment |
Supplementation |
|
| $73,000.00 |
$3,000.00 |
$3,000 Supplement per year of participation in DTRA CBD-supported NRC tenure at USAMRIID
|
Experience Supplement:
Postdoctoral and Senior Associates will receive an appropriately higher stipend based on the number of years of experience past their PhD.
|