Opportunity at U.S. Army Medical Research & Materiel Command (AMRMC)
Adjuvant and Antigen Research
Walter Reed Army Institute of Research, Infectious Diseases-Military HIV Research Program
||Silver Spring, MD 20910
|Matyas, Gary R.
This program features research on novel methods of delivery including transcutaneous immunization and development of adjuvants and liposomes as carriers of vaccines. It also includes oil-in-water emulsions, the immunology of lipids, and lipid metabolism of cultured cells. Additional areas of research include (1) development of antiviral vaccines, particularly HIV; (2) creation of monoclonal antibodies to lipids, proteins, and peptides; (3) studies on biological and biochemical effects of adjuvants and immunomodulators; (4) studies on chemistry, immunology, and biology of endotoxin and lipid A; (5) intracellular fate of liposomes and liposomal antigens; (6) mechanisms of immunologic presentation of liposomal antigens; and (7) interaction of HIV-1 with cells and development of novel assays for HIV-1 neutralization.
Brown BK, et al: Journal of Virology 81: 2087, 2007
Karasavvas N, et al: Biochemical Biophysical Research Communications 366: 982, 2008
Neutralizing antibodies; HIV; Intracellular trafficking; Adjuvants; Cellular immunology; Transcutaneous immunization; Liposomes; Lipid rafts; Antigens; Vaccines;
Open to U.S. citizens, permanent residents and non-U.S. citizens
Open to Postdoctoral and Senior applicants