The National Academies Logo
Research Associateship Programs
Fellowships Office
Policy and Global Affairs

Participating Agencies - AMRMC

  Sign InPrintable View

Opportunity at U.S. Army Medical Research & Materiel Command (AMRMC)

Adjuvant and Antigen Research

Location

Walter Reed Army Institute of Research, Infectious Diseases-Military HIV Research Program

RO# Location
97.15.70.B3399 Silver Spring, MD 20910

Advisers

Name E-mail Phone
Matyas, Gary R. Gary.r.matyas.civ@mail.mil 301.319.9973

Description

This program features research on novel methods of delivery including transcutaneous immunization and development of adjuvants and liposomes as carriers of vaccines. It also includes oil-in-water emulsions, the immunology of lipids, and lipid metabolism of cultured cells. Additional areas of research include (1) development of antiviral vaccines, particularly HIV; (2) creation of monoclonal antibodies to lipids, proteins, and peptides; (3) studies on biological and biochemical effects of adjuvants and immunomodulators; (4) studies on chemistry, immunology, and biology of endotoxin and lipid A; (5) intracellular fate of liposomes and liposomal antigens; (6) mechanisms of immunologic presentation of liposomal antigens; and (7) interaction of HIV-1 with cells and development of novel assays for HIV-1 neutralization.

 

References

Brown BK, et al: Journal of Virology 81: 2087, 2007

Karasavvas N, et al: Biochemical Biophysical Research Communications 366: 982, 2008

 

Keywords:
Neutralizing antibodies; HIV; Intracellular trafficking; Adjuvants; Cellular immunology; Transcutaneous immunization; Liposomes; Lipid rafts; Antigens; Vaccines;

Eligibility

Citizenship:  Open to U.S. citizens, permanent residents and non-U.S. citizens
Level:  Open to Postdoctoral and Senior applicants
Copyright © 2014. National Academy of Sciences. All rights reserved. 500 Fifth St. N.W., Washington, D.C. 20001.
Terms of Use and Privacy Statement.