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RAP Lab Opportunities at NIST

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Opportunity at National Institute of Standards and Technology (NIST)

Computational Metrology for Systems Biology and Medicine


Information Technology Laboratory, Software and Systems Division

RO# Location
50.77.51.B7527 Gaithersburg, MD

Please note: This Agency only participates in the February and August reviews.


Name E-mail Phone
Bajcsy, Peter peter.bajcsy@nist.gov 301.975.2958
Sriram, Ram D. sriram@nist.gov 301.975.3507


Systems biology involves gathering comprehensive sets of data that define and quantify the elements of a particular biological system and computationally analyzing these data sets to establish functional and dynamic connections. The premise is that no molecule in biology acts alone. There are thousands of cause-and-effect interactions that occur. Understanding of those interactions and their effect on the biological system is enabled through massive integration of data–experimental and theoretical. Systems biology in a clinical context is called systems medicine. Representative research areas of interest in systems biology and medicine are standards for sharing data across different hardware, software, operating systems, etc; tools that will aid in data collection at a volume and quality that is consistent with the use of statistical methods; machine learning techniques for knowledge discovery; protein-protein interaction network analysis; novel algorithms for next generation DNA sequencing; evaluation and testing ontologies for describing and organizing biological and medical information; and languages for capturing bio-informatics analyses and computational processes


Systems biology; Machine learning; Statistical methods; Ontologies; Testing; Next generation DNA sequencing; Protein-protein interaction networks; Standards;


Citizenship:  Open to U.S. citizens
Level:  Open to Regular applicants
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