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RAP Lab Opportunities at NIST

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Opportunity at National Institute of Standards and Technology (NIST)

Smart Nanoagents for Magnetic Resonance Imaging

Location

Physical Measurement Laboratory, Electromagnetics Division

RO# Location
50.68.72.B7933 Boulder, CO

Please note: This Agency only participates in the February and August reviews.

Advisers

Name E-mail Phone
Russek, Stephen russek@boulder.nist.gov 303.497.5097

Description

Ultrasmall magnetic structures will be fabricated using both conventional nanolithography (e-beam lithography) and chemical synthetic techniques. The goal will be to engineer the dynamical properties of these nanomagnets to give enhanced MRI T1 contrast, allow in-vivo activation of the agents, provide unique functionality, and mimic endogenous agents in both their natural and diseased states. Examples include developing nanosystems with MRI-excitable resonances, large thermal and mechanical response to RF fields, and RF-stimulated chemical activation. We are also interested in biomimetic iron oxide agents that mimic healthy and pathologic tissue and whose state can report on local metabolic processes. This work will use the NIST-Boulder cleanroom, 7 T MRI scanner, variable-field NMR system, broadband EPR system, and SQUID/VSM magnetometers.

 

Keywords:
Contrast agents; Electron spin resonance; Ferromagnetic resonance; Magnetic nanoagents; MRI; Nanomagnetism;

Eligibility

Citizenship:  Open to U.S. citizens
Level:  Open to Regular applicants
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