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RAP Lab Opportunities at NIST

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Opportunity at National Institute of Standards and Technology (NIST)

Ferritin and Other Magnetic Nanoparticles in Protein Shells

Location

Physical Measurement Laboratory, Electromagnetics Division

RO# Location
50.68.72.B6628 Boulder, CO

Please note: This Agency only participates in the February and August reviews.

Advisers

Name E-mail Phone
Goldfarb, Ron B. goldfarb@boulder.nist.gov 303.497.3650

Description

Ferritin is nature’s ubiquitous iron-storage molecule, found in species ranging from microbes to man. It consists of a roughly spherical apoferritin protein shell, inside which iron accumulates in the form of a ferric oxyhydroxide crystal. The outer diameter is 12 nm, irrespective of the amount of iron stored within. Although its physical, chemical, and magnetic properties have been studied for more than 60 years, ferritin remains a subject of current research, with many implications for biology and medicine. In particular, ferritin is an important contributor to T1 and T2 relaxation, which effectively determine image contrast in magnetic resonance imaging. Applicants with backgrounds in physical chemistry, chemical synthesis, magnetochemistry, magnetometry, nuclear magnetic resonance, and electron paramagnetic resonance are invited to apply. Equipment available includes a SQUID magnetometer, a variable-field nuclear magnetic resonance system, and a small-bore MRI system.

 

Keywords:
Ferritin; Magnetic nanoparticles; Magnetic resonance imaging; Magnetic contrast agents;

Eligibility

Citizenship:  Open to U.S. citizens
Level:  Open to Regular applicants
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