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Opportunity at National Institute of Standards and Technology (NIST)

Electronic and Optomechanical Measurements of Biomolecules

Location

Physical Measurement Laboratory, Engineering Physics Division

RO# Location
50.68.31.B8326 Gaithersburg, MD

Please note: This Agency only participates in the February and August reviews.

Advisers

Name E-mail Phone
Balijepalli, Arvind arvind.balijepalli@nist.gov 301.975.3526

Description

The chemical characterization of biomolecules and the measurement of their interactions at low copy numbers are critical for applications in biomanufacturing and personalized medicine. We are developing new electronics techniques that leverage field effects and strain, and optomechanical interferometric methods for the on-chip measurements of molecular interactions and spectroscopic characterization of proteins, nucleic acids, small molecule ligands, and other biomolecules. We work closely with theoretical and simulation groups to realize device designs. In addition to fabrication and characterization of these measurement tools, we also develop new readout schemes, signal and data processing, control systems, and biomimetic surfaces to improve the selectivity of our measurements. Opportunities are available in device design and fabrication, biomolecule measurements and biophysics, biomimetic surfaces, and readout and signal processing.

 

References

Balijepalli A, et al: Journal of the American Chemical Society 135(18): 7064-7072, 2013

Balijepalli A, et al: ACS Nano 8(2): 1547-1553, 2014

Paulechka E, et al: Nanoscale 8: 1861-1867, 2016

 

Keywords:
Biosensing; Electronics; Optomechanics; Spectroscopy; Interferometry; Binding affinity; Signal processing; Biophysics; FET;

Eligibility

Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral applicants
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