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RAP Lab Opportunities at NIST

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Opportunity at National Institute of Standards and Technology (NIST)

DNA Transport in Single Nanopores

Location

Physical Measurement Laboratory, Semiconductor and Dimensional Metrology Division

RO# Location
50.68.31.B4789 Gaithersburg, MD

Please note: This Agency only participates in the February and August reviews.

Advisers

Name E-mail Phone
Kasianowicz, John J. john.kasianowicz@nist.gov 301.975.5853
Robertson, Joseph William joseph.robertson@nist.gov 301.975.2506

Description

We are studying the mechanism by which DNA partitions into and threads through single nanometer-scale pores. This experimental and theoretical effort focuses on understanding how genetic information is exchanged between organisms (e.g., between virus and host cells or between bacteria) and on adapting single nanopores for novel biological and biotechnological applications. It was recently shown that the interaction between polymers and a single nanopore provides the physical basis of a multi-analyte sensor. Work is also underway to determine whether this system could be used as tool to rapidly sequence long strands of DNA and RNA.

 

Keywords:
Biosensors; DNA; Membranes; Proteins;

Eligibility

Citizenship:  Open to U.S. citizens
Level:  Open to Regular applicants
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