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Metrology for Genome Editing


Material Measurement Laboratory, Biosystems and Biomaterials Division

RO# Location
50.64.41.B8400 Gaithersburg, MD

Please note: This Agency only participates in the February and August reviews.


Name E-mail Phone
Maragh, Samantha Denise 301.975.4947


Genome editing technologies enable targeted DNA sequence changes to be made in the cells organisms. Genome editing is being actively pursued to transform precision medicine and bioscience in areas such as cell therapy, synthetic biology, novel antimicrobials and antivirals, protein therapeutic biomanufacturing, agriculture, and global food production. Moving the promise of these technologies into production and precision medicine requires high confidence characterization of the genome editing pipeline, particularly as it pertains to the generation of intended and unintended DNA sequence changes. The genome editing community recognizes this is a critical need, which is difficult to address. Research will focus on developing tools, robust quantitative assays, and reliable measurement infrastructure to meet measurement assurance needs for the genome editing field.


Gene editing; Biology; CRISPR; Cas9; Genetics; Genome; Molecular; Cell; Precision medicine;


Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral applicants
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