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Protein Aggregation


Material Measurement Laboratory, Materials Science and Engineering Division

RO# Location
50.64.21.C0328 Gaithersburg, MD

Please note: This Agency only participates in the February and August reviews.


Name E-mail Phone
Hudson, Steven David 240.688.7883


Microscopic fluid dynamics at surfaces lead to irreversible protein aggregation; this is a concern for biomanufacturing. Controlling temperature, interface chemistry and shear rate will help decouple the interplay between thermodynamics, interfacial adsorption, and hydrodynamic deformation and transport during the kinetics of protein aggregation. In-situ measurements of adsorption (structure and amount) and particle characterization will determine formation mechanisms.

Protein solutions; Monoclonal antibodies; Interfacial adsorption; Optical microscopy; Microfluidics; Neutron scattering;


Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral applicants


Base Stipend Travel Allotment Supplementation
$72,030.00 $3,000.00
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