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Opportunity at U.S. Environmental Protection Agency (EPA)

An Integrated Genomics Approach to Assessing Human and Ecological Health in Aquatic Systems

Location

National Exposure Research Laboratory, Systems Exposure Division (OH)

RO# Location
22.01.08.B7967 Cincinnati, OH 45268

Advisers

Name E-mail Phone
Villegas, Eric N villegas.eric@epa.gov 513.569.7017

Description

A senior fellowship opportunity is available at the US Environmental Protection Agency’s (EPA) National Exposure Research Laboratory (NERL) in Cincinnati, OH. This appointment will be served in the Microbiological and Chemical Exposure Assessment Research Division (MCEARD). The fellowship is part of an EPA effort to use fundamental advancements in genomic tools and our deepening understanding of the breadth of microbial diversity to develop the microbiome as a tool for assessing watershed integrity, both in terms of ecosystem structure/function and human health impacts from waterborne disease. The microbiome is relatively simple to analyze and if patterns/ markers within this community be consistently related to traditional measures of ecosystem health (i.e., macrobenthic invertebrate index) and human health risks (presence of indicators of fecal contaminants or human pathogens themselves) then it may be a more efficient, unifying approach for aquatic monitoring. Initial development of this approach is leveraging the on-going National Rivers and Streams Assessment (NRSA); filtered water samples from over 2000 river and stream locations were collected as part of NRSA are being delivered to NERL laboratories for molecular analysis. Metagenomic profiles of the microbiome of these samples are being mined for relationships to the range of other state descriptors collected as part of the NRSA. The Associate will work with the MCEARD team to process/analyze/publish results from this on-going study and to assist in further development of the conceptual framework for this new research area.

 

Keywords:
Metagenomics; Sequencing; Bioinformatics; Nucleic acids; Microbiome; Microbial diversity;

Eligibility

Citizenship:  Open to U.S. citizens, permanent residents and non-U.S. citizens
Level:  Open only to Senior applicants
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