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Opportunity at U.S. Environmental Protection Agency (EPA)

Bioaccessibility and Bioavailability of Metals in Contaminated Soils

Location

National Exposure Research Laboratory, Exposure Methods & Measurement Division (NC)

RO# Location
22.01.03.B7049 Research Triangle Park, NC 27711

Advisers

Name E-mail Phone
Bradham, Karen bradham.karen@epa.gov 919 541 9414

Description

NERL’s Method Development and Applications Branch has a research opportunity to investigate the bioavailability of metals including nanomaterials and explore the relationship of metal bioaccessibility and bioavailability in environmental media. This research effort will complement ongoing research to develop techniques to investigate the bioavailability of nanomaterials,elucidate the speciation of metals in soils, and relate metal speciation and soil characteristics to bioavailability. Work will involve (1) evaluating the bioavailability of nanomaterials, (2) building a data base of in-vitro bioaccessibility data using an extraction test to assess the potential bioavailability of metals in soils, (3) development of in-vitro bioaccessibility extractions tests to assess the potential bioavailability of arsenic in soil, (4) research in support of in-vivo animal feeding studies, and (5) evaluation of the relationship between the bioavailability and bioaccessibility results. Knowledge of metal bioavailability and chemistry in soils is necessary. Development of improved extraction methods, in vivo models, and laboratory analyses will be encouraged.

 

References

Bradham KD, et al: Environmental Health Perspectives 119: 1629, 2011 http://dx.doi.org/10.1289/ehp.1003352

Van de Wiele T, et al: Environmental Health Perspectives 118: 1004, 2010 http://dx.doi.org/10.1289/ehp.0901794

 

Keywords:
Bioavailability; Bioaccessibility; In vitro; In vivo; Solubility; Soils; Lead; Soil chemistry; Arsenic;

Eligibility

Citizenship:  Open to U.S. citizens, permanent residents and non-U.S. citizens
Level:  Open to Postdoctoral and Senior applicants
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