Opportunity at Air Force Research Laboratory (AFRL)
Ultrafast Spectroscopic Investigations on the Mechanisms of Interaction of Modified Sensing Proteins with the Electromagnetic Spectrum
Airman Systems Directorate, RHD/Bioeffects Division
||Fort Sam Houston, TX 78234
|Schmidt, Morgan Steele
The main objective of this research is to study the effect of directed energy on biological material and determine the resulting impact. To support this mission, this opportunity includes the development of new ultrafast spectroscopic techniques for the investigation of protein interaction with a range of the electromagnetic spectrum (EM). In addtion, our team has the following spectral capabilities: 2DIR, UV/VIS - NIR Transient Absorption Spectroscopy (fs/ps time scales), FTIR, UV/VIS absorption. Specifically, we are interested in the use of non-traditional EM frequencies (NIR, IR, RF) in order to move towards a non-invasive optogenetic approach. Our group collaborates with various AFRL laboratories to focus on both the molecular mechanisms, as well as whole cell models, for the development of new, protein-based sensing elements. Molecular simulations, coupled with ultrafast spectroscopic techniques, will be performed in order to validate the engineered proteins as well as provide novel capabilities to AFRL. The laboratory offers extensive laser facilities that operate in the VIS-IR range, as well as MHz-GHz frequency sources. Selected candidates should expect to help design and build optical experiments, collect and analyze complex spectral data, and collaborate with AFRL staff. Understanding of empirical MD simulations and density functional theory (DFT), time-dependent DFT (TDDFT), as well as quantum calculations is also desired.
Spectroscopy; Physical chemistry; Chemistry; Molecular dynamics; Biochemistry; Protein dynamics; Optics; Nanoparticles; Optogenetics;
Open to U.S. citizens
Open to Postdoctoral and Senior applicants
$3,000 Supplement for Doctorates in Engineering & Computer Science
Postdoctoral and Senior Associates will receive an appropriately higher stipend based on the
number of years of experience past their PhD.