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Opportunity at U.S. Army CCDC Chemical Biological Center (CCDC CBC)

Cell-free Biomanufacturing

Location

U.S. Army CCDC - Chemical Biological Center, Life Sciences, Medical Sciences, & Behavioral Sciences

RO# Location
11.01.04.C0560 Aberdeen Proving Ground, MD 210105423

Advisers

Name E-mail Phone
Lux, Matthew matthew.w.lux.civ@army.mil 410-436-1448

Description

Biomanufacturing is increasingly being viewed as an important tool to provide alternative and flexible domestic manufacturing capabilities for an agile supply chain. These technologies promise to boost the economy and secure domestic supply of important products, such as medicines or fuels. Traditionally, the vast majority of biomanufacturing efforts use cells in bioreactors to simultaneously grow and produce target products from cheap feedstocks. Cell-free systems are an emerging alternative in which cells are grown first and their expression and metabolic machinery harvested, followed by manufacturing of products using the extracted machinery. This approach has several advantages to cell-based manufacturing, including reduced sensitivity to products that inhibit growth, ability to produce products that are larger than the size of a cell, and rapid design and testing cycles that circumvent cloning. We are seeking NRC candidates that can support our efforts in cell-free biomanufacturing. Qualified candidates will have experience in cell-free systems, biomanufacturing, metabolic engineering, fermentation scale-up, microbiology, or synthetic biology; ideal candidates will have experience in both cell-free systems and biomanufacturing. Candidates will need to be flexible and willing to adapt to multiple roles within a large and evolving program.

Keywords:
Cell-free systems; biomanufacturing; synthetic biology; metabolic engineering; scale-up engineering

Eligibility

Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral and Senior applicants

Stipend

Base Stipend Travel Allotment Supplementation
$72,750.00 $3,000.00

$5,000 Supplement for Doctorates in Engineering & Computer Science

$4,050 Supplement for each year of experience in the DTRA CBD-funded NRC tenure at CCDC.

Experience Supplement:
Postdoctoral and Senior Associates will receive an appropriately higher stipend based on the number of years of experience past their PhD.

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