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Opportunity at Defense Forensic Science Center (DFSC)

Enhancing Sexual Assault Investigations

Location

Defense Forensic Science Center

RO# Location
09.01.01.B8232 Forest Park, GA 302975205

Advisers

Name E-mail Phone
Salyards, Jeff michael.j.salyards.civ@mail.mil 404.469.7107

Description

Forensic Bodily Fluid Typing Using NGS

To reach our objectives, the Defense Forensic Science Center (DFSC), under the Office of the Chief Scientist (OCS), is developing Next-Generation Sequencing (NGS) techniques for advanced forensic DNA identification. In addition to the identification of a contributor in a sample, there is an enormous wealth of information hidden in forensic stains that can provide information about a suspect’s activity via body fluid typing. Body fluid typing, via RNA analysis, can identify saliva, seminal fluid, vaginal fluid, menstrual blood, peripheral blood, and urine. Currently, the identification of bodily fluids carried out through mRNA analysis is capillary electrophoresis (CE) or high resolution melt (HRM) methods and consumes a portion of the forensic sample. A single workflow using NGS instrumentation to analyze RNA and DNA simultaneously for the detection of bodily fluid type and identification of an individual would potentially save time and cost. This may be achieved by researching NGS methods, the use of RNA markers in the instrumentation, and simultaneous analysis of DNA and RNA markers, or more novel approaches. Discovery of new body fluid markers may be necessary. The novel methods generated from this research project will result in a paradigm shift in the analysis of forensic samples. Prospective applicants should have a strong background in Informatics, Genomics, Mathematics, Numerical Methods, and/or Statistics. The strongest candidates will be comfortable with DNA analysis, but application is not limited to this background.

 

Keywords:
Informatics; Genomics; DNA; RNA; Biochemistry; Statistics; Chemistry; Next-generation sequencing (NGS); Biology; Forensics;

Eligibility

Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral applicants
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