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Opportunity at Chemical and Biological Defense Funded Laboratories (CBD)

Selective Methods for C-X Activation

Location

ARO-US Army Research Office-Duke University, US Army Research Office-Duke University

RO# Location
01.04.01.B7038 Durham, NC 277039142

Advisers

Name E-mail Phone
Becker, Jennifer J. jennifer.j.becker.civ@mail.mil 919.549.4224

Description

This research focuses on the exploration of selective methods for C-X activation. We perform experimental mechanistic studies to predict the stereochemical outcome of transition metal catalyzed transformations, including oxidative addition. Studies are also performed to determine the mechanisms of transformations and to distinguish among SN2-like displacements, free radical intermediates, and ionic processes. The influence of substrate structure and metal on the rate and selectivity of oxidative additions are assessed. Our goal is to understand the fundamental properties that govern reactivity and selectivity and to determine selective reaction pathways for the catalytic functionalization of complex natural molecules, including carbohydrates.

 

Keywords:
Organometallic; Oxidative addition; Transition metal catalysts;

Eligibility

Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral applicants
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